Brian Tham is a biotechnology executive and CMC consultant with more than 25 years of leadership experience across the pharmaceutical and biotech industries. He specializes in biologics, vaccines, cell and gene therapy, and CMC program development, with deep expertise spanning manufacturing, process development, regulatory strategy, and global supply chain operations.
As Principal of Peregrine Bio, Brian provides strategic planning, R&D portfolio management, and CMC program governance support to biotechnology organizations. He advises clients on process development, technology transfer, manufacturing readiness, regulatory compliance, risk management, and facility design, helping organizations accelerate development while maintaining operational excellence and quality standards.
Throughout his career, Brian has held senior leadership roles at Novavax, GlaxoSmithKline (GSK), and Human Genome Sciences, where he directed complex CMC programs, manufacturing outsourcing initiatives, and cross-functional product development teams. He has successfully led global development strategies, technology transfers, commercial manufacturing readiness programs, and regulatory inspection preparation efforts across multiple therapeutic platforms.
Brian has extensive experience managing outsourced development and manufacturing networks, overseeing cGMP operations, optimizing supply chains, and building scalable processes that support product development from early-stage research through commercialization. His expertise includes biologics manufacturing, vaccine development, regulatory filings, process automation, strategic sourcing, and quality and compliance systems.
Known for his collaborative leadership style, Brian excels at aligning technical, operational, and business objectives to drive program execution, mitigate risk, and deliver measurable results in highly regulated environments.
Brian earned an M.B.A. from Georgetown University, a B.S. in Microbiology and Immunology from the University of British Columbia, and holds Project Management Professional (PMP) certification from the Project Management Institute.